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NADPH, derived from glucose via the PPP, is the ultimate electron donor that reduces the downstream proteins in the GSH antioxidant system

Dose-dependent effect of buthionine sulfoximine on total glutathione level

Medications like Ozempic, Mounjaro, and Trulicity work by mimicking the GLP-1 hormone, which increases insulin secretion, slows gastric emptying, and reduces appetite. However, these benefits come with a high price tag, prompting some individuals to seek compounded versions. While compounded alternatives may seem like the same medication at a fraction of the cost, they come with significant risks. Brand Name GLP-1 Medications Brand name GLP-1 medications have undergone thorough testing to receive FDA-approval

Leveraging this natural mechanism to enhance the endogenous secretion of GLP-1 presents a promising avenue for managing T2D

Interventions All patients received 100 mg of sertraline (Tehran-Daru Pharmaceutical Company, Iran) daily along with either 1000 mg carnitine (Vana-Darougostar Pharmaceutical Company, Iran) or placebo (cooking starch), prepared in identical capsules