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Therefore, TAG hydrolysis appears independent of NHR-49, which is further supported by the unaltered expression of critical lipolysis regulators, hormone sensitive lipase, hosl-1 , and the adipose triglyceride lipase, atgl-1 , in nhr-49(nr2041) mutant animals (Supplementary Fig

Trends Biotechnol

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doi: 10.1007/978-3-7643-8340-4_6 48

It is an important concept in pharmacology because it helps determine how long a compound remains active and how frequently it may need to be administered

H 2 O 2 /O/OH are essential in initiating the ICD response by detecting oxidative stress and activating the ICD pathway