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It is overexpressed in the adipose tissue of obese and diabetic individuals

First-line obesity treatments include lifestyle intervention (e.g., low-calorie diets) and behavioral modification therapies 4,5 since approved obesity medications have limited efficacy and commonly have side effects 6

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The criteria below reflect the standards clinics commonly use during an initial evaluation, though a full medical assessment always determines the final answer

No dose-ranging study has established a human oral dose for this compound, so the high oral numbers circulate as community and vendor convention rather than as published clinical figures