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Icariin reverses corticosterone-induced depression-like behavior, decrease in hippocampal brain-derived neurotrophic factor (BDNF) and metabolic network disturbances revealed by NMR-based metabonomics in rats

Both of these compounds also help balance enzymes that control collagen breakdown

Safety considerations such as insulin sensitivity concerns with certain CLA isomers and the TMAO question for L-carnitine matter for some people

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The site claims the product is made locally and approved by the Therapeutic Goods Administration (TGA)