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In vivo studies have shown that R162 prevents lung cancer metastasis in patient-derived xenograft models (Jin et al., 2018)

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[PubMed] [CrossRef] Walter JH

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Nonetheless, our study demonstrates that a persistent imbalance between oxidative stress toxicity and reduced ANTIOX is a key component of Long COVID and that increased aldehyde, neutrophil-associated MPO, protein carbonyl, and NO production are the major neurotoxic pathways, which, when combined with decreased ANTIOX, may have a variety of detrimental effects as reviewed before [81]

Similarly, Parkinsons disease is associated with alterations in gut microbiota composition, particularly a reduction in anti-inflammatory taxa such as Akkermansia muciniphila