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While mechanistically interesting, stacking three or more compounds dramatically increases complexity, cost, and potential for unexpected interactions

Given the scoping nature of the review and the heterogeneity of available evidence, study selection focused on identifying representative and clinically informative literature rather than exhaustive quantitative inclusion

Expander This appliance is commonly referred to as a bonded upper expander and consists of a palatal expansion screw with metal arms that are within the wire framework

Synthetic In addition to being found naturally in foods, alpha-tocopherol can also be synthesized

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