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Measurable Outcomes to Track Changes in the Modified Obstructed Defecation Syndrome (MODS) score

[1] Suspected side effects should be reported via the MHRA Yellow Card scheme

The study medication was stored in a study refrigerator and protected from light until 30 min before administration, when it was allowed to come to room temperature, for participant comfort during administration

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It should be noted that GCLM KO mice have systemic GSH deficiencies, ranging from 10 to 40% of normal levels depending on the tissue type 16