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Clinical trial data in humans indicate that exenatide or liraglutide may have a role in the treatment of T2DM as monotherapy or in addition to oral antidiabetic drugs

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Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial

Cystinosis stands as a prototypic disorder for a subgroup of lysosomal storage diseases caused by defective lysosomal transporters [2]

Crucially, Crat knockout experiments partially reversed these metabolic improvements, establishing CrAT-mediated SREBP1c inhibition as a key mechanism through which L-carnitine counteracts de novo lipogenesis