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One focus of the recent research is into the long-term interaction of GIP and GLP-1 receptor signalling, which could potentially be clarified if a long-acting GIP receptor agonist, which has already been investigated in rodent studies [24,25], can also be studied in humans
doi: 10.1016/j.cmet.2012.04.004 147 TobiumeKMatsuzawaATakahashiTNishitohHMoritaKTakedaKet al
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Grafts can fail, and prostheses can irritate mucosa and supporting tissues
Some patients also pursue liposuction to refine stubborn areas that remain resistant to weight loss
