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Access this article Similar content being viewed by others Data availability The datasets generated and/or analyzed during the current study are not publicly available due to legal/commercial restrictions but are available from the corresponding author on reasonable request
Cancer Cell 27 (2), 257270
GHS can mildly increase insulin resistance and glycated hemoglobin (HbA1c) levels over time
Interestingly, a recent study has also identified ERMCSs as required for lipid radical transfer from mitochondria to the ER to reduce mitochondrial oxidative stress 87 , which could represent another mechanism stimulated by ERMCS-localised GLP-1R to enhance -cell survival under glucolipotoxic conditions
Some high risk groups for vitamin B12 deficiency include: elderly people- often stomach acid production decreases with age individuals who have had intestinal surgery such as weight loss surgery or laparoscopies individuals with GI issues including celiac disease, IBD, IBS (MOST OF YOU!!!) those following a vegetarian or vegan diet- due to the lack of animal protein eaten (one of the main sources of B12) individuals with pernicious anemia- do not make intrinsic factor Notice how a fair amount of the high risk individuals are those with some sort of intestinal issue
