Cell Mol Biol (Noisy-le-Gd)
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Clinical studies are investigating the potential of lipid peroxidation inducers in cancer treatment, with agents such as sorafenib demonstrating effectiveness in hepatocellular carcinoma via using oxidative stress mechanisms
Another report showed that autophagic responses were significantly diminished in OLETF rats after experimental myocardial infarction associated with a deficiency in AMPK/ULK-1 activation, Akt/mTOR/S6 signaling, and increased Beclin-1-Bcl-2 interaction, which are key molecular events for suppressing autophagy
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JT: Conceptualization, Data curation, Formal Analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing original draft, Writing review and editing