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However, PCO rates within the first year of surgery have greatly diminished over the past 10 years due to the widespread introduction of square edge hydrophobic IOLs that sequester remnant LECs and their derivatives in Soemmerings ring which resides outside of the optical axis (73, 74, 107, 292)

When to seek medical attention: Patients should call 999 immediately for severe allergic reactions (facial swelling, breathing difficulties, widespread rash)

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Inskeep PB et al

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Chronically elevated insulin, visceral fat, systemic inflammation, and oxidative stress are deeply intertwined with the hallmarks of aging (like cellular senescence and mitochondrial dysfunction)