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Thursdays readout could cast an even longer shadow of doubt over Novos obesity pipeline, particularly after the disappointing Phase II results for its small molecule oral cannabinoid receptor 1 agonist monlunabant, which in September showed modest weight reductions muddied by psychiatric side effects
Eluted fractions consisting of complex were pooled and concentrated to ~4 mg/mL and flash frozen by liquid nitrogen as aliquots and stored at 80 C until use
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The overall gene expression pattern shifted cells from a profile associated with diseased or damaged tissue toward a healthier state
