At the American College of Cardiology meetings today, with simultaneous publication in NEJM, was a new randomized trial of semaglutide in 616 participants with heart failure with preserved ejection fraction, obesity and Type 2 diabetes
MAOIs (monoamine oxidase inhibitors) like phenelzine or tranylcypromine don't have significant absorption interaction with tirzepatide, but patients on MAOIs face dietary restrictions that can complicate the appetite suppression tirzepatide induces
Fluoxetine has little to no effects on many of these other chemicals besides serotonin, whereas Zoloft and Cymbalta can also affect the levels of norepinephrine and dopamine in your brain
GLP-1 side effects should settle down over time, not spiral into bigger problems
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