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The relative expression levels were calculated with three technical replicates using the 2 Ct method

Avoid using harsh exfoliants or retinoids for a few days prior to treatment to minimize sensitivity

Check the product Instructions for Use for specific guidance on how long to keep the pen out of refrigeration before use

Each plasmid contained DNA encoding the class 1 IGF-1 48-amino acid signal peptide, the mature 70-amino acid IGF-1 peptide, the first 16 aa common in all E-domains, and C-terminal sequences encoding either the Ea (19 aa), the Eb (61 aa) or the Ec (24 aa) domain

Patients should consult a qualified healthcare provider before starting any peptide therapy program

Another consideration involves glycemic variability in patients using semaglutide for diabetes management