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Precision obesity medicine matching patients to specific GLP-1 mechanisms based on genetic predictors, gut microbiome profiles, and metabolic phenotyping represents an emerging differentiation opportunity

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Methods This was a randomised, single-centre, multiple-dose, open-label, five-armed, parallel-group trial in healthy subjects who received once-daily oral semaglutide (3 mg for 5 days followed by 7 mg for 5 days)

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