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The main practical disadvantages are: poor absorption in standard capsule form, the need for consistent daily use over 8-12+ weeks before visible results, relatively higher cost for well-absorbed formats, mild and uncommon side effects like digestive discomfort or headache in some users, and the risk of unrealistic expectations from aggressive marketing claims
In short, glutathione has shown benefit among cystic fibrosis and AIDS patients who have decreased glutathione in the intestine, and it may show benefit in inflammatory conditions of the intestine, such as ulcerative colitis and Crohns disease, but this needs to be studied as well
But more research is needed to know if NAC has a big benefit for people with HIV or AIDS
What to Expect: Timeline and Results GHK-Cu works through biological processes that take time collagen remodeling is not instantaneous