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These cytokines can also cross the blood-brain barrier, driving the severe neuroinflammation responsible for the profound cognitive dysfunction, memory loss, and "brain fog" reported by so many patients

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doi: 10.3389/fendo.2021.645566 Received 23 December 2020 Accepted 15 March 2021 Published 29 March 2021 Volume 12 - 2021 Edited by Francesco Giorgino, University of Bari Aldo Moro, Italy Reviewed by Georgios K

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Environmental exposure, DNA methylation, and gene regulation