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Because structured weight management programs have been shown to lower AF burden, this indirect benefit may be significant

Between .7 and 1g/lb is a practical benchmark worth shooting for

There is insufficient evidence at this time that other modifications in the HD prescription or various components of the HD treatment enhance ESA therapy

However, it is still an investigational medicine, and important questions remain about its long-term safety, durability of weight loss and effectiveness across different patient groups

Sinclair J, McClain D, Taetle R

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