This raises a major red flag: when financial gain becomes the primary goal, patient well-being can get lost in the shuffle
Glutamine (Gln) metabolism in macrophage polarization is mainly manifested as a composite regulatory axis of TCA cycle anaplerosis-mitochondrial metabolism-epigenetic coupling. Its role is usually not reflected by the output of a single effector molecule, but rather by the coordinated shaping of polarization-related transcriptional programs through metabolic flux and key intermediates, particularly -KG (59)
Lakhdar H, Zouhair K, Khadir K, Essari A, Richard A, Seite S, et al
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and ZAPATA-SUDO, G., 2022
The Renfrew Center