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Journal of Cosmetics, Dermatological Sciences and Applications (2019)

doi: 10.1172/jci.insight.133429 26 Barreto-ViannaARCAguilaMBMandarim-de-LacerdaCA

Make sure you are losing fat, not muscle

The evidence shows that while GLP-1s RA like semaglutide provide an important metabolic foundation, the best fertility results occur when they are paired with healthy lifestyle choices

Underlying conditions affecting fertility : If you have PCOS, irregular periods, or other reproductive health concerns, your healthcare provider can assess whether weight loss through GLP-1 treatment might benefit your fertility and discuss alternative or complementary approaches

For a broader view of which peptides have achieved regulatory approval, see our pillar article: FDA Approved Peptides List 2026