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Dinkla S, Peppelman M, Van Der Raadt J, Atsma F, Novotn VM, Van Kraaij MG, et al
Januvia is a DPP-4 inhibitor that blocks the enzyme breaking down natural incretin hormones, whilst Rybelsus is a GLP-1 receptor agonist that directly mimics incretin action
Inflammation Modulation BPC-157-induced inflammation is supported by studies showing modulation of immune and inflammatory signaling pathways
Instead, it combines appropriate medical therapy with foundational metabolic repair
Across diabetes and obesity, there are ~20 novel GLP-1 agonists and multi-agonists in Phase 2/3 development (see image 2) , with a host more in earlier stages
SGLT-2 inhibitors also modestly lower blood pressure (comparable to the introduction of a thiazide diuretic), reduce albuminuria and induce modest weight loss
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