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Product Monograph Including Patient Medication Information Rybelsus semaglutide tablets (PDF) (Report)
However, GLP-1R agonists elicit nausea and vomiting 6,10 , and increase mean heart rate via directly stimulating sinoatrial node and enhancing sympathetic nervous system tone 10,11,12
Modified versions of GLP-1 have been developed to be more potent and have longer-lasting effects, and they are currently used in clinical practice to treat type-2 diabetes
Lebrun LJ, Lenaerts K, Kiers D, Pais de Barros JP, Le Guern N, Plesnik J, et al
Regular monitoring is key
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