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In heart failure with preserved ejection fraction (HFpEF) with obesity, SUMMIT demonstrated a 38% reduction in the composite of cardiovascular death and worsening heart failure, complementing the STEP-HFpEF program [5], [20], [21]

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We further demonstrated that these genes are concordantly differentially expressed in previous cross-sectional studies involving larger numbers of individuals with varying degrees of airflow limitation

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Coles B, Zaccardi F, Hvid C, Davies MJ, Khunti K

James: I want people to understand that eating less does not inherently mean you eat well