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[15] This signal has not been confirmed in humans, but it is reflected in the prescribing information for approved GLP-1-based medicines such as semaglutide (see the UK Summary of Product Characteristics for Wegovy, available via the electronic Medicines Compendium)

Long-term risks of Trulicity include the potential worsening of or new onset kidney damage and severe digestive problems such as gastroparesis or ileus

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Tirzepatide has demonstrated significant weight loss efficacy in clinical trials, leading to its approval for chronic weight management

XZ, YL, DW, TL, ZX, ZL, XB and YW contributed to the design of the study and writing of the manuscript