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These include: Nausea Vomiting Diarrhoea Constipation Decreased appetite (which, whilst therapeutically intended, can occasionally be excessive) Injection-site reactions (such as redness, bruising, or discomfort at the injection site) These effects were generally mild to moderate in severity and most frequently occurred during the dose-escalation phase of treatment, tending to diminish over time

Convenient 30ml vial lasts 4 weeks

doi:10.1517/13543784.15.11.1299

Biopsy is often necessary to differentiate the lesion from a nevus or a melanoma

Injections bypass the gastrointestinal tract and are the standard treatment for pernicious anaemia and severe deficiency in the UK