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SGLT2 inhibitor users had the highest rates of hypertension and cardiovascular disease, whereas women prescribed GLP-1R agonists were more likely to be obese or suffer from polycystic ovarian syndrome (PCOS)
In the 1950s, fewer than 10% of Americans had obesity
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The MHRA has approved these medications for specific indications, and NICE guidelines recommend their use in adults with type 2 diabetes who meet certain criteria (NG28)
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