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In female germ cells, telomerase ensures the correct replication of DNA sequences, and telomere length and activity are closely related to oocyte quality

Concurrently, ROS oxidatively modify tau protein, enhancing its hyperphosphorylation and subsequent aggregation into neurofibrillary tangles, thereby disrupting microtubule stability and axonal transport [334]

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27 Under hypoxic conditions, intervened by hypoxia-inducible factor (HIF), there is a reduction in hepcidin expression, which promotes iron release

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