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1 The LEADER trial (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome ResultsA Long-Term Evaluation), a large double-blind, placebo-controlled trial, recently demonstrated that liraglutide added to standard therapy for a relatively short period of time (3.5-5 years) had a significant reduction in cardiovas-cular events and mortality compared to placebo in high-risk patients (hazard ratio [HR], 0.87

Where pharmacist prescribing exists for chronic disease management (HIV PrEP, smoking cessation, hormonal contraception), the GLP-1 expansion would typically require additional authorization

Omega-3 supplementation complements these effects through independent anti-inflammatory, triglyceride-lowering, and cardioprotective mechanisms

McCarty, a gastroenterologist and researcher at Houston Methodist who led the study

doi: 10.1148/radiol.14141079 49 BuchwaldDCheneyPRPetersonDLHenryBWormsleySBGeigerAet al