For healthy individuals, the recommended vitamin B12 intake is 2.4 to 2.8 micrograms (mcg) per day
Actual fat loss follows from weeks three or four onwards at the starter dose, accelerating as the dose increases
The most common side effects include temporary dryness, slight redness, or increased photosensitivity
It belongs to a class of medicines known as dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonists
A later review framed the molecule honestly as a still unresolved riddle, conceding that decades of study had not pinned down a mechanism or a confirmed physiological role (PMID 16539679)
Taken together, our data indicate that the loss of GSH triggered by Gclc deletion induces a defective mitochondrial accumulation in FoB, which may lead to compensation through upregulation of glycolytic metabolism