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We confirmed both in vitro and in vivo that specific combination of ligands of different transporters, especially alanine and glutathione, is more efficient than single ligands to facilitate the penetration of nanocarrierss across the BBB [24, 32, 33, 42]

Gustav Fischer (1901)

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Also in livestock (boars), retarded sexual development was shown with Se excess in feed, with a gradual decline in sperm production (85, 169)