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Dec 29 2021;15(1)doi:10.3390/ph15010046
Reductive carboxylation A process that occurs in some normal and cancer cells whereby -ketoglutarate proceeds 'backwards' through the tricarboxylic acid cycle, being reduced through the consumption of NADPH by isocitrate dehydrogenase in the non-canonical reverse reaction to form citrate
Liu J, Hong M, Li Y, et al
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