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Prescribing a GLP-1 medication specifically to treat alcohol use disorder would be off-label use

It took he and his team nine years to achieve the goal

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In this field, a crucial inflammatory factor, IL-1, was observed downregulated by Lactobacillus gasseri NK109 with the simultaneous upregulated expression of brain-derived neurotrophic factor (BDNF) in the hippocampus of mice with cognitive impairment and depression induced by Escherichia coli K1, suggesting its alleviation in brain inflammation against neuropsychiatric disorders caused by bacterial infection [86]