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Alpha lipoic acid has been used as a therapeutic agent in humans, esp

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Mutant TDP-43 activates M1 microglia and upregulates pro-inflammatory mediators NOX2, TNF-, and IL-1 (Beers et al., 2011

As an extension of the above, the brains high metabolic rate and oxygen consumption make it vulnerable to oxidative stress, which can lead to aging and neurodegenerative diseases like Alzheimers and Parkinsons Disease

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143, no