In select cases particularly patients with: Obesity High insulin resistance Very high total daily insulin requirements endocrinologists may consider off-label use with: Continuous glucose monitoring Routine ketone monitoring Strict sick-day protocols Close specialist follow-up But this is not standard therapy
However, like all medicines, oral Semaglutide can cause side-effects
Many users fall short on fiber intake, leading to increased GI symptoms and reduced production of short-chain fatty acids (SCFAs), which are critical for GLP-1 activation and signaling
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During your visit, ask questions and make sure the surgeon makes you feel comfortable
Sources STEP 1 trial (semaglutide 2.4 mg) - NEJM, "Once-Weekly Semaglutide in Adults with Overweight or Obesity"