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The ruthenium(II)arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53JNK pathways
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Notably, elevated levels of lipid peroxidation are reliably detected in brain tissues and body fluids of Alzheimers, Parkinsons, Huntingtons disease, motor neuron disease and multiple sclerosis patients ( Since its original characterisation in cancer cells, the concept of ferroptosis has instigated growing efforts to explicitly detect and measure its footprint in neurodegeneration ( in vitro
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