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In 2004, researchers conducted a meta-analysis of 61 randomized controlled trials evaluating GLP-1 RAs, sodium-glucose co-transporter-2 inhibitors (SGLT2i), dipeptidyl peptidase 4 inhibitors (DPP-4i) and didnt find an increased risk of diabetic retinopathy events with GLP-1 RAs or any of the other classes of antihyperglycemic medications
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, et al
Clinical data indicates that roughly 4050% of the blood pressure benefit from GLP-1 therapy stems from direct metabolic effects, while the remaining improvements reflect weight reduction and improved insulin sensitivity
Comparison of established menstrual cycles Although no participants had amenorrhea, oligomenorrhea was prevalent among certain participants at study enrollment
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