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doi: 10.3389/fpsyt.2024.1491417 Received 04 September 2024 Accepted 29 October 2024 Published 12 November 2024 Volume 15 - 2024 Edited by Mirko Manchia, University of Cagliari, Italy Reviewed by Francesco Monaco, Azienda Sanitaria Locale Salerno, Italy Kristen Ward, University of Michigan, United States Updates Copyright 2024 Fitzgerald, Sahm, N Dhubhlaing, ODwyer, OConnell, Torrens and Crowley
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BPC-157 is a 15-residue, 1419.53 g/mol pentadecapeptide whose mechanistic literature centres on local angiogenic signalling, Hsieh and colleagues (J Mol Med, 2017) reported upregulation and internalisation of VEGFR2 in human endothelial cells, and Chang and colleagues (J Appl Physiol, 2011) reported increased FAK and paxillin phosphorylation with greater outgrowth and migration in cultured rat tendon fibroblasts
The process is brief and generally well tolerated
In Trial 2, the mean AHI at baseline was 49.5 events/hour
10.1177/1945892419878315 Am J Rhinol Allergy
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