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doi: 10.1142/S0192415X25500326 133 XuHWangLYanKZhuHPanHYangHet al

On the right, the selenium-dependent glutathione peroxidase oxidizes two molecules of GSH back to GSSG in a reaction that converts one molecule of hydrogen peroxide (H 2 O 2 ) into two molecules of water (H 2 O)

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Gene therapy has shown promise in animal models of thalassemia, and clinical trials are underway (Payen 2012