This process involved metabolic dysfunction that results in increased production of cytosolic and lipid ROS, independently of mitochondria
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Presynaptic cytoplasmic Ca 2+ can be depleted by several complementary mechanisms, including sarcoendoplasmic reticulum Ca 2+ -ATPase (SERCA) to the endoplasmic reticulum (ER), plasma membrane Ca 2+ -ATPase to the extracellular space, and MCU to the mitochondrial matrix [51,52,53]
Farr OM, Tsoukas MA, Triantafyllou G, Dincer F, Filippaios A, Ko BJ, et al
Le dosi variano da 1.000-4.000 mg al giorno
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