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Chauhan A, Chauhan V, Brown WT, Cohen I
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Medically reviewed by Timothy Wilson, MD, Shawn Price, MD, David McConda, MD, and Philip Stickney, MD - May 2026
In this study, the IGF-1 receptor inhibitor AG1024 increased the response of resistant cancer cells to docetaxel and decreased the expression of TUBB2B, highlighting the potential of targeting the IGF-1 axis as a novel therapeutic strategy
Among these alleles, 4 were obtained from lines collected before the use of DDT and so it is unlikely that the G171K change occurred in response to DDT selection