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In a 12-month study of 339 Second Nature members published in JMIR Formative Research, members taking tirzepatide (Mounjaro) lost an average of 22.1% of their body weight, and those taking semaglutide (Wegovy) lost 17.1%, in line with the averages seen in the original clinical trials

The effect of exenatide on thyroid-stimulating hormone and thyroid volume

Ipamorelin is a selective growth hormone secretagogue that stimulates GH release without significantly affecting cortisol or prolactin levels

Some patients losing access to their compounded medications are considering switching over to generic liraglutide, an older GLP-1 medication that's known to be less effective than semaglutide or tirzepatide

Gut health influences inflammation, hormone signaling, microbiome composition, and nutrient metabolism, all of which can impact metabolic function

2018 Jan 9;9(1):113