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It plays a central role in detoxification, immune function, DNA synthesis and repair, enzyme activity and the regulation of oxidative stress
GSLs, the precursors of ITCs, constitute in addition to their role in defence responses a storage for reduced sulfur as well as a good example on how the partitioning of this macronutrient is controlled between primary and secondary metabolism 82
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Bax oligomerization is associated with the formation of openings in the OMM to allow the release of cytochrome c and other IMS proteins into the cytosol, and hence Bax oligomerization is considered a critical regulatory point in cell death (Youle and Strasser, 2008)
