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GLP-1 receptor agonists, including semaglutide and tirzepatide, were originally developed to treat type 2 diabetes

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In contrast, cutaneous lesions are linked directly to fair-skinned and blue-eyed persons with a history of blistering sunburns, and incidence has increased dramatically over the same time period

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Novo responded the same day, publicly characterizing the product as "illegal mass compounding that poses a significant risk to patient safety." On February 6, the FDA announced it would take action against companies mass-marketing unapproved compounded GLP-1 products, and HHS General Counsel stated publicly that the department had referred Hims to the DOJ for potential FDCA violations