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The transcription factor cAMP response element modulator (CREM) is highly expressed in male germ cells and regulates the expression of several post-meiotic genes, such as the transition proteins and protamines, and it likely is the key regulator of gene expression during spermatogenesis
We interrogated gene expression changes in more detail focusing on pathways involved in cellular glucose handling: Glycolysis, TCA Cycle, Oxidative Phosphorylation ( Figures 5DF )
Wang ST et al
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Glycosphingolipid synthesis mediates immune evasion in KRAS-driven cancer
Real-world data shows that 70-80% of patients feel a significant energy surge within 24-72 hours
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