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First description in humans of the ability of SGLT2 inhibitors to attenuate glomerular hyperfiltration, likely by affecting tubuloglomerular feedback mechanisms

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Fewer than one-third of patients had T2D

IGF-1 (Insulin-like Growth Factor 1) is the downstream mediator responsible for most of GHs anabolic and lipolytic effects

Tan HC et al

Subgroup = 23 patients with progression of the infection (CT Scan)