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In the years immediately following the IOMs 1998 report setting the current RDA, research associated an abnormally high level of homocysteine, a molecule involved in protein metabolism, with an increased risk of cardiovascular disease, mortality, and cognitive impairment
In the trials, individuals with diabetes lost less weight with these medications than those without diabetes
Lang CA, Naryshkin S, Schneider DL, Mills BJ, Lindeman RD
Brain (2018) 141(7):191733
Nephrol Dial Transplant 2017;32:97-110.ArticlePubMed 27
These trials enrolled different populations under different protocols, so the percentages are not a head-to-head ranking
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