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Eating less can also play a role
The Quinlan 2022 study at 0.2mm with twice-weekly cadence is the closest signal we have, and it is a small (n=11) open-label study
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GLP-1 acts through its receptors, GLP-1R, which is expressed in different tissues, including the pancreas, heart, kidney, adipose, and central nervous system
It includes multiple trials studying retatrutide in different patient populations and for different indications
(PubMed) Xu R, Zhang S, Tao A, Chen G, Zhang M
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