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This is an individualized prescription decision, not a general TBI recommendation

Hamasaki K et al

It is an imbalanced agonist with GIPR potency close to native GIP but weaker GLP-1R affinity, and shows biased GLP-1R signaling, favoring cAMP over -arrestin recruitment

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The treatment requires multiple sessions (typically 510), costs between 40,000 and 1,20,000 for optimal results, and demands ongoing maintenance every 23 months

PMID 26087744