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Frequently Asked Questions Glossary References Jastreboff AM, Kaplan LM, Frias JP, et al

The completion rate for patients randomized into the extension phase of Study 2 was 81%

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Serious side effects of semaglutide In rare cases , semaglutide can cause serious side effects, including : Acute pancreatitis Acute gallbladder disease Acute kidney injury Allergic reaction Diabetic retinopathy Heart rate increase Severe hypoglycemia Suicidal behavior and ideation Finally, animal studies have shown that semaglutide led to the development of thyroid tumors in rats

If you notice increased anxiety at bedtime or racing thoughts , consider seeking support from your GP or a mental health professional

Updated June 20, 2025